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Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) MYH11 Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02422
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC, IF, IHC
Clon ID8
Specific against Human (Homo sapiens), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Guinea Pig, Chicken (Gallus gallus domesticus), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus), Cat (Feline, Felis catus), Cow (Bos taurus)
Host Mouse
Isotype IgG1 Kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Myosin-11;Myosin heavy chain 11;Myosin heavy chain, smooth muscle isoform;SMMHC;MYH11;KIAA0866;
Lieferbar
Manufacturer - Category
Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight
227339 MW
Clonality
Monoclonal
Application Details
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name
MYH11
Gene Full Name
Myosin-11
Background
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Immunogen
Human uterus extract
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration
Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category
Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Motor Proteins, Myosin, Signal Transduction
Protein Function
Muscle contraction.
Subcellular Localization
Cytoplasmic
Short Description
Boster Bio Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) MYH11 Monoclonal Antibody (Catalog # M02422). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Cow, Pig, Dog, Cat, Rabbit, Rat, Guinea pig, Chicken.
Description
Boster Bio Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) (Leiomyosarcoma & Myoepithelial Cell Marker) MYH11 Monoclonal Antibody (Catalog # M02422). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Cow, Pig, Dog, Cat, Rabbit, Rat, Guinea pig, Chicken.
Tissue Specificity
Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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