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Anti-Atg4B Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02885
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC
Clon ABIA-1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <50pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cysteine protease ATG4B;3.4.22.-;AUT-like 1 cysteine endopeptidase;Autophagin-1;Autophagy-related cysteine endopeptidase 1;Autophagy-related protein 4 homolog B;hAPG4B;ATG4B;APG4B, AUTL1, KIAA0943;
Lieferbar
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
50 kDa
Calculated Molecular weight
44294 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
FC 1:100
Manufacturer - Gene Name
ATG4B
Gene Full Name
Cysteine protease ATG4B
Immunogen
A synthesized peptide derived from human Atg4B
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cancer, Cardiovascular, Cell Biology, Cell Death, Extracellular Matrix, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Protein Function
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Subcellular Localization
Cytoplasm.
Description
Boster Bio Anti-Atg4B Rabbit Monoclonal Antibody catalog # M02885. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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