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Anti-Beta Tubulin TUBB Antibody Picoband® (monoclonal, 2E11)

Anti-Beta Tubulin TUBB Antibody Picoband® (monoclonal, 2E11)

ArtNr	BOS-M05613-4
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug 100 ug 100 ug 100 ug/vial 100 ug/vial 100 ug/vial 100 ug/vial
Kategorie	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cytoskeleton Flow Cytometry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Mikrotubules Neurodegeneration Markers Immunochemistry
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	WB, FC, IF, ICC
Clon	2E11
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Sensitivity	>5000 cells
Citations	1. Entrez Gene: TUBB tubulin, beta. 2. Volz A, Weiss E, Trowsdale J, Ziegler A (Jan 1994). Presence of an expressed beta-tubulin gene (TUBB) in the HLA class I region may provide the genetic basis for HLA-linked microtubule dysfunction. Human Genetics. 93 (1): 42–6.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tubulin beta chain,Tubulin beta-5 chain,TUBB,TUBB5,OK/SW-cl.56
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	55 kDa
Clonality	Monoclonal
Application Details	Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2μg/ml, Human Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
Gene Name	TUBB
Gene Full Name	tubulin beta class I
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Tubulin beta chain is a protein that in humans is encoded by the TUBB gene. This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human Beta Tubulin, identical to the related mouse and rat sequences.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500μg/ml.
Manufacturer - Research Category	Cell Adhesion Proteins, Epigenetics and Nuclear Signaling, Integrins, Mediator Complex, Neuroscience, Receptors, Transcription
Protein Function	Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Subcellular Localization	cytoskeleton
Description	Boster Bio Anti-Beta Tubulin TUBB Antibody Picoband® (monoclonal, 2E11) catalog # M05613-4. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M05613-4-datasheet.pdf

BOS-M05613-4-safety-datasheet.pdf