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Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

ArtNr	BOS-M10708
Hersteller	Boster
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC-P
Clon	Anto-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	p53-induced death domain-containing protein 1;Leucine-rich repeat and death domain-containing protein;PIDD1;LRDD, PIDD;
Lieferbar
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Store at -20°C for long-term storage. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Observed Molecular Weight	99712 MW
Clonality	Monoclonal
Application Details	Western Blot (1:500). Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot. Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.
Manufacturer - Gene Name	PIDD1
Gene Full Name	p53-induced death domain-containing protein 1
Immunogen	Recombinant human PIDD death domain (aa 776-910)
Contents	Liquid. In PBS containing 0.02% sodium azide.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Name	p53-induced death domain-containing protein 1 (PIDD1)
Protein Function	Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways.
Subcellular Localization	Cytoplasm. Nucleus.
Short Description	Boster Bio Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1) (Catalog# M10708). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1) (Catalog# M10708). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse.
Tissue Specificity	Ubiquitous.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M10708-datasheet.pdf

BOS-M10708-safety-datasheet.pdf