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Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

Item no.	BOS-M10708
Manufacturer	Boster
Amount	100 ug
Category	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC-P
Clone	Anto-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	p53-induced death domain-containing protein 1;Leucine-rich repeat and death domain-containing protein;PIDD1;LRDD, PIDD;
Available
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Store at -20°C for long-term storage. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Observed Molecular Weight	99712 MW
Clonality	Monoclonal
Application Details	Western Blot (1:500). Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot. Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.
Manufacturer - Gene Name	PIDD1
Gene Full Name	p53-induced death domain-containing protein 1
Immunogen	Recombinant human PIDD death domain (aa 776-910)
Contents	Liquid. In PBS containing 0.02% sodium azide.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Name	p53-induced death domain-containing protein 1 (PIDD1)
Protein Function	Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways.
Subcellular Localization	Cytoplasm. Nucleus.
Short Description	Boster Bio Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1) (Catalog# M10708). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1) (Catalog# M10708). Tested in IHC-P, WB application(s). This antibody reacts with Human, Mouse.
Tissue Specificity	Ubiquitous.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M10708-datasheet.pdf

BOS-M10708-safety-datasheet.pdf