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Anti-Cytokeratin, pan (Epithelial Marker) Antibody Europäischer Partner

ArtNr BOS-M30944
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, FC, IF, IHC
Clon PAN-CK (Cocktail)
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian), Rabbit (Oryctolagus cuniculus), Chicken (Gallus gallus domesticus), Dog (Canine, Canis lupus familiaris), Cat (Feline, Felis catus), Cow (Bos taurus)
Host Mouse
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
Lieferbar
Manufacturer - Category
Monoclonal Antibodies, Primary Antibodies
Manufacturer - Isotype
IgG s, kappa
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight
51386 MW
Clonality
Monoclonal
Application Details
Flow Cytometry (0.5-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Western Blot (0.5-2ug/ml for 2 hours at RT)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name
KRT
Gene Full Name
keratin 77
Background
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad-spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.
Immunogen
Human epidermal keratins
Contents
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Purification
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration
Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category
Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction
Protein Name
Keratin, type II cytoskeletal 1b
Subcellular Localization
Cytoplasmic
Short Description
Boster Bio Anti-Cytokeratin, pan (Epithelial Marker) Antibody (Catalog # M30944). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Cat, Chicken.
Description
Boster Bio Anti-Cytokeratin, pan (Epithelial Marker) Antibody (Catalog # M30944). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Cat, Chicken.
Tissue Specificity
Expressed exclusively in skin.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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