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Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody

Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody

ArtNr	BOS-M30950-2
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Metabolism Glucose Homeostasis Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	GBG-5
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Epithelial cell adhesion molecule;Ep-CAM;Adenocarcinoma-associated antigen;Cell surface glycoprotein Trop-1;Epithelial cell surface antigen;Epithelial glycoprotein;EGP;Epithelial glycoprotein 314;EGP314;hEGP314;KS 1/4 antigen;KSA;Major gastrointestinal tumor-associated protein GA733-2;Tumor-associated calcium signal transducer 1;CD326;EPCAM;GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1;
Lieferbar
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	50 kDa
Calculated Molecular weight	34932 MW
Clonality	Monoclonal
Application Details	WB 1:1000-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	EPCAM
Gene Full Name	Epithelial cell adhesion molecule
Immunogen	A synthesized peptide derived from human EpCAM
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cell Type Markers, Tags & Cell Markers, Tumor Associated
Protein Function	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Subcellular Localization	Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Description	Boster Bio Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody catalog # M30950-2. Tested in WB, IHC applications. This antibody reacts with Human.
Tissue Specificity	Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M30950-2-datasheet.pdf

BOS-M30950-2-safety-datasheet.pdf