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Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10) Europäischer Partner

ArtNr BOS-MA1052
Hersteller Boster
Menge 100 ug/vial
Quantity options 100 ug/vial 10 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Applikationen IHC
Clon K36AC10
Specific against Human (Homo sapiens), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus)
Host Mouse
Isotype IgG1
Sensitivity >5000 cells
Sequence Belongs to the insulin family.
Citations 1. Harper, M. E.; Ullrich, A.; Saunders, G. F. : Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Proc. Nat. Acad. Sci. 78: 4458-4460, 1981.
2. Owerbach, D.; Bell, G. I.; Rutter, W. J.; Shows, T. B. : The insulin gene is located on chromosome 11 in human. Nature 286: 82-84, 1980.
3. Huerre, C.; Gilgenkrantz, S.; Leonard, C.; Pictet, R.; Kaplan, J. C.; Junien, C. : Regional assignment of the structural gene for insulin to 11p15.1-11p15.5 by deletion mapping. (Abstract) Cytogenet. Cell Genet. 37: 495, 1984.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Insulin-2,Insulin-2 B chain,Insulin-2 A chain,Ins2,Ins-2
Similar products ILPR, IRDN, IDDM2, PROINSULIN, MODY10, Insulin2, Ins-2
Lieferbar
Manufacturer - Category
Primary Antibodies, Mouse Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
70 kDa
Calculated Molecular weight
12339 MW
Clonality
Monoclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.4-1μg/ml, Human, rabbit, rat
Gene Name
INS
Gene Full Name
Insulin-2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Insulin, synthesized by the beta cells of the islets of Langerhans, consists of 2 dissimilar polypeptide chains, A and B, which are linked by 2 disulfide bonds. The insulin gene contains 3 exons and 2 introns; exon 2 encodes the signal peptide, the B chain, and part of the C peptide, while exon 3 encodes the remainder of the C peptide and the A chain. Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Harper et al. (1981) and Harper and Saunders (1981) assigned the insulin gene to 11p15.5 by in situ hybridization.
Immunogen
Human insulin.
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Purification
Ascites
Reconstitution
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Concentration
Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Manufacturer - Research Category
Cancer, Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction, Tumor Biomarkers
Protein Name
Insulin
Protein Function
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Insulin Ins2 Antibody (Monoclonal, K36AC10) catalog # MA1052. Tested in IHC applications. This antibody reacts with Human, Rabbit, Rat.
Sequence Similarities
Belongs to the insulin family.
Manufacturer - Cross Reactivity
No cross-reactivity with other proteins

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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