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Anti-Tenascin TNN Antibody (Monoclonal, BC-24)

Anti-Tenascin TNN Antibody (Monoclonal, BC-24)

ArtNr	BOS-MA1094
Hersteller	Boster
Menge	100 ug/vial
Quantity options	100 ug/vial 10 ug
Kategorie	Neuroscience Metabolism Diabetes Regulation of Appetite Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Necrosis Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Lyophilized
Applikationen	WB, IHC, ICC
Clon	BC-24
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Sensitivity	<10 pg/ml
Sequence	Belongs to the tenascin family.
Citations	1. Saga, Y.; Yagi, T.; Ikawa, Y.; Sakakura, T.; Aizawa, S. : Mice develop normally without tenascin. Genes Dev. 6: 1821-1831, 1992. 2. Gulcher, J. R.; Alexakos, M. J.; Le Beau, M. M.; Lemons, R. S.; Stefansson, K. :Chromosomal localization of the human hexabrachion (tenascin) gene and evidence for recent reduplication within the gene. Genomics 6: 616-622, 1990. 3. Gulcher, J. R.; Nies, D. E.; Alexakos, M. J.; Ravikant, N. A.; Sturgill, M. E.; Marton, L. S.; Stefansson, K. : Structure of the human hexabrachion (tenascin) gene. Proc. Nat. Acad. Sci. 88: 9438-9442, 1991.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Protein Tnn,Tnn
Similar products	Tenascin
Lieferbar
Manufacturer - Category	Primary Antibodies, Mouse Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	272 kDa
Calculated Molecular weight	173250 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 2-4μg/ml, Human Immunocytochemistry , 1μg/ml, Human, - Immunohistochemistry (Frozen Section), 2-4μg/ml, Human, - Western blot, 1-2μg/ml, Human
Gene Name	TNN
Gene Full Name	tenascin N
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	The tenascins are a family of extracellular matrix proteins (ECMs). Tenascin is an extracellular matrix protein. It expressed in an unusually restricted pattern during embryogenesis and has been implicated in a variety of morphogenetic phenomena. Human hexabrachion gene (tenascin) is mapped to chromosome 9, bands q32-q34. The coding region of the hexabrachion gene spans approximately 80 kilobases of DNA and consists of 27 exons separated by 26 introns.
Immunogen	Human tenascin.
Contents	Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Purification	Ascites
Reconstitution	Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Concentration	Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.
Manufacturer - Research Category	Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction
Protein Name	Tenascin-N
Protein Function	TNN: Involved in neurite outgrowth and cell migration inhippocampal explants.
Subcellular Localization	TNN: Secreted, extracellular space, extracellularmatrix.\|Tnn: Secreted, extracellular space, extracellularmatrix.
Description	Boster Bio Anti-Tenascin TNN Antibody (Monoclonal, BC-24) catalog # MA1094. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Tissue Specificity	Expressed in neurons. The larger forms (isoform tau-A and isoform tau-B) are preferentially expressed in the peripheral nervous system while the other are expressed in the central nervous system. Low amounts of the larger forms are also found in limited areas of the CNS.
Sequence Similarities	Belongs to the tenascin family.
Manufacturer - Cross Reactivity	No cross-reactivity with other proteins

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BOS-MA1094-datasheet.pdf

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