Anti-STAT5 phospho Y694 STAT5A Monoclonal Antibody

Store STAT5 phospho Y694 Antibody at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Phospho STAT5 antibody is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Monoclonal

ELISA: 1:20, 000
IHC: 20-40 µg/ml
IF Microscopy: 1:50-1:1000
WB: 1:500 - 1:2, 000

Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5? ?and Stat5ß. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus. Ideal for Cancer, Chromatin & Nuclear Signaling and Signal Transduction research.

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

1.0 mg/mL by UV absorbance at 280 nm

Boster Bio Anti-STAT5 phospho Y694 STAT5A Monoclonal Antibody (Catalog # MP01087). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse.