Anti-MRGX1/MRGPRX1 Antibody Picoband®

ArtNr	BOS-PA1208
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Cardiovascular Research Atherosclerosis Hypertension Primary Antibodies Other Lipid\Cholesterol Metabolism Modulators
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IHC
Specific against	Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mas-related G-protein coupled receptor member X1;Sensory neuron-specific G-protein coupled receptor 1;Mrgprx1;Mrgc, Mrgprc, Mrgprc11, Snsr, Snsr1;
Similar products	G protein coupled receptor MRGX1 antibody, G protein coupled receptor SNSR3 antibody, GPCR antibody, Mas related G protein coupled receptor member X1 antibody, MAS related gene MRGX1 antibody, MAS related GPR member X1 antibody, MRGPRX1 antibody, MRGX1 antibody, Sensory neuron specific G protein coupled receptor 3/4 antibody, Seven transmembrane helix receptor antibody, SNSR3 antibody, SNSR4 antibody
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	49 kDa
Calculated Molecular weight	37074 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Rat, By Heat Western blot, 0.1-0.5?g/ml, Rat
Manufacturer - Gene Name	MRGPRX1
Gene Full Name	Mas-related G-protein coupled receptor member X1
Background	MAS-related G-protein coupled receptor, member C, also known as MRGPRC or MRGPRX1, is a human gene. The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of rat MRGX1.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name	Mas-related G-protein coupled receptor member X1
Protein Function	Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G (q) and G (11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception (By similarity).
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Description	Boster Bio Anti-MRGX1/MRGPRX1 Antibody catalog # PA1208. Tested in IHC, WB applications. This antibody reacts with Rat.
Tissue Specificity	Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors).
Sequence Similarities	Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

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