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Anti-D-dopachrome decarboxylase DDT Antibody Picoband®

Anti-D-dopachrome decarboxylase DDT Antibody Picoband®

ArtNr	BOS-PA1449
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Lung Cancer Colorectal Cancer Breast Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
Citations	1. Esumi, N., Budarf, M., Ciccarelli, L., Sellinger, B., Kozak, C. A., Wistow, G.Conserved gene structure and genomic linkage for D-dopachrome tautomerase (DDT) and MIF.Mammalian Genome 9: 753-757, 1998. 2. Nishihira, J., Fujinaga, M., Kuriyama, T., Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I., Sakai, M.Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.Biochem. Biophys. Res. Commun. 243: 538-544, 1998.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	D-dopachrome decarboxylase;4.1.1.84;D-dopachrome tautomerase;Phenylpyruvate tautomerase II;DDT;
Similar products	D dopachrome decarboxylase antibody, D dopachrome tautomerase antibody, D-dopachrome decarboxylase antibody, D-dopachrome tautomerase antibody, DDCT antibody, Ddt antibody, Phenylpyruvate tautomerase II antibody
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	13-15 kDa
Calculated Molecular weight	12712 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat
Manufacturer - Gene Name	DDT
Gene Full Name	D-dopachrome decarboxylase
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	DDT, D-dopachrome tautomerization, converts D-dopachrome into 5, 6-dihydroxyindole. Northern blot analysis revealed that DDT was expressed as a 0.6-kb mRNA in all tissues tested, with the strongest expression in liver. The DDT gene in human and mouse is identical in exon structure to the MIF gene. Both genes have 2 introns that are located at equivalent positions, relative to a 2-fold repeat in protein structure.the genes for DDT and MIF are closely linked on human chromosome 22 and mouse chromosome 10.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human DDT, different from the related mouse and rat sequence by two amino acids.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Cell Biology
Protein Name	D-dopachrome decarboxylase
Protein Function	Tautomerization of D-dopachrome with decarboxylation to give 5, 6-dihydroxyindole (DHI).
Subcellular Localization	Cytoplasm.
Description	Boster Bio Anti-D-dopachrome decarboxylase DDT Antibody catalog # PA1449. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Sequence Similarities	Belongs to the intercrine alpha (chemokine CxC) family.

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BOS-PA1449-datasheet.pdf

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