Anti-Dopamine Receptor D3/DRD3 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

44225 MW

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Rat, Human, Mouse, By Heat
Western blot, 0.1-0.5?g/ml, Human, Rat, Mouse

D(3) dopamine receptor

DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Neuroscience, Neurotransmission, Receptors / Channels

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.

Boster Bio Anti-Dopamine Receptor D3/DRD3 Antibody catalog # PA1584. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Belongs to the G-protein coupled receptor 1 family.