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Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Hersteller Boster
Kategorie
Typ Elisa-Kit
Specific against Human
Applikationen ELISA
Menge For 5 plates, 96 wells each
ArtNr BOS-EZ0702
Targets CD40
eClass 6.1 32160605
eClass 9.0 32160605
Lieferbar
Manufacturers Product Category
EZ-Set™ ELISA Kits (Ab Pairs)
Manufacturers Research Category
Lymphoid, Myeloid, Stem Cells, Vascular Inflammation
Short Description
Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CD40 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Description
Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CD40 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Background
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B-cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells. The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Gene Name
CD40
Immunogen
Expression system for standard: NS0; Immunogen sequence: E21-R193
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Sample Type
cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Storage
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant
heparin or EDTA
Gene Full Name
Tumor necrosis factor receptor superfamily member 5
Molecular Weight
30619 MW
Protein Function
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Subcellular Localization
Isoform I: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
B-cells and in primary carcinomas.
Protein Name
Tumor necrosis factor receptor superfamily member 5
Sequence Similarities
Contains 4 TNFR-Cys repeats.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: For 5 plates, 96 wells each
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 13.06.2024 

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