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Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Manufacturer Boster
Category
Type Elisa-Kit
Specific against Human
Applications ELISA
Amount For 5 plates, 96 wells each
Item no. BOS-EZ0702
Targets CD40
eClass 6.1 32160605
eClass 9.0 32160605
Available
Manufacturers Product Category
EZ-Set™ ELISA Kits (Ab Pairs)
Manufacturers Research Category
Lymphoid, Myeloid, Stem Cells, Vascular Inflammation
Short Description
Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CD40 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Description
Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CD40 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Background
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B-cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells. The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
Gene Name
CD40
Immunogen
Expression system for standard: NS0; Immunogen sequence: E21-R193
Cross-reactivity
There is no detectable cross-reactivity with other relevant proteins.
Sample Type
cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk.
Storage
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant
heparin or EDTA
Gene Full Name
Tumor necrosis factor receptor superfamily member 5
Molecular Weight
30619 MW
Protein Function
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Subcellular Localization
Isoform I: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
B-cells and in primary carcinomas.
Protein Name
Tumor necrosis factor receptor superfamily member 5
Sequence Similarities
Contains 4 TNFR-Cys repeats.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: For 5 plates, 96 wells each
Available: In stock
available

Delivery expected until 6/13/2024 

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