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MART-1 Colorimetric Cell-Based ELISA Kit

MART-1 Colorimetric Cell-Based ELISA Kit

ArtNr	BOS-EKC1352
Hersteller	Boster
Menge	1 kit, containing one 96-well plate and all necessary reagents
Kategorie	Oncology By Cell Type Melanoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay Immunostaining
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Melanoma antigen recognized by T-cells 1,MART-1,Melan-A protein,Antigen SK29-AA,Antigen LB39-AA,MLANA,MART1
Lieferbar
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Molecular Weight	13157 MW
Gene Name	MLANA
Gene Full Name	Melanoma antigen recognized by T-cells 1
Protein Function	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Subcellular Localization	Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Description	The MART-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MART-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MART-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MART-1.
Tissue Specificity	Expression is restricted to melanoma and melanocyte cell lines and retina.
Sample Type	Cell lines

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-EKC1352-datasheet.pdf

BOS-EKC1352-safety-datasheet.pdf