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MART-1 Colorimetric Cell-Based ELISA Kit

MART-1 Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC1352
Manufacturer	Boster
Amount	1 kit, containing one 96-well plate and all necessary reagents
Category	Oncology By Cell Type Melanoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay Immunostaining
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Melanoma antigen recognized by T-cells 1,MART-1,Melan-A protein,Antigen SK29-AA,Antigen LB39-AA,MLANA,MART1
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Molecular Weight	13157 MW
Gene Name	MLANA
Gene Full Name	Melanoma antigen recognized by T-cells 1
Protein Function	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Subcellular Localization	Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post- Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Description	The MART-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MART-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of MART-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MART-1.
Tissue Specificity	Expression is restricted to melanoma and melanocyte cell lines and retina.
Sample Type	Cell lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC1352-datasheet.pdf

BOS-EKC1352-safety-datasheet.pdf