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Calsenilin/KCNIP3 (Phospho-Ser63) Colorimetric Cell-Based ELISA Kit Europäischer Partner

ArtNr BOS-EKC2283
Hersteller Boster
Menge 1 kit, containing two 96-well plates and all necessary reagents
Kategorie
Typ Elisa-Kit
Applikationen ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity >5000 cells
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias A-type potassium channel modulatory protein 3;CSEN;DRE-antagonist modulator;DREAM;KCNIP3;KChIP3;Kv channel-interacting protein 3
Lieferbar
Manufacturer - Category
Cell-Based ELISA Kits
Storage Conditions
Store at 4°C for up to 6 months.
Observed Molecular Weight
29231 MW
Manufacturer - Gene Name
KCNIP3
Gene Full Name
Calsenilin
Sample Type
Cell lines
Protein Function
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity).
Subcellular Localization
Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
Short Description
The Calsenilin/KCNIP3 (Phospho-Ser63) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calsenilin/KCNIP3 (Phospho-Ser63) protein expression profile in cells. The kit can be used for measuring the relative amounts of Calsenilin/KCNIP3 (Phospho-Ser63) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calsenilin/KCNIP3 (Phospho-Ser63).
Description
The Calsenilin/KCNIP3 (Phospho-Ser63) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calsenilin/KCNIP3 (Phospho-Ser63) protein expression profile in cells. The kit can be used for measuring the relative amounts of Calsenilin/KCNIP3 (Phospho-Ser63) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calsenilin/KCNIP3 (Phospho-Ser63).
Tissue Specificity
Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 kit, containing two 96-well plates and all necessary reagents
Lieferbar: In stock
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