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Calsenilin/KCNIP3 (Phospho-Ser63) Colorimetric Cell-Based ELISA Kit

Calsenilin/KCNIP3 (Phospho-Ser63) Colorimetric Cell-Based ELISA Kit

Item no.	BOS-EKC2283
Manufacturer	Boster
Amount	1 kit, containing two 96-well plates and all necessary reagents
Category	Cell Biology Cell Status ELISA Autophagy ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Applications	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	A-type potassium channel modulatory protein 3;CSEN;DRE-antagonist modulator;DREAM;KCNIP3;KChIP3;Kv channel-interacting protein 3
Available
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	29231 MW
Manufacturer - Gene Name	KCNIP3
Gene Full Name	Calsenilin
Sample Type	Cell lines
Protein Function	Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity).
Subcellular Localization	Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
Short Description	The Calsenilin/KCNIP3 (Phospho-Ser63) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calsenilin/KCNIP3 (Phospho-Ser63) protein expression profile in cells. The kit can be used for measuring the relative amounts of Calsenilin/KCNIP3 (Phospho-Ser63) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calsenilin/KCNIP3 (Phospho-Ser63).
Description	The Calsenilin/KCNIP3 (Phospho-Ser63) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calsenilin/KCNIP3 (Phospho-Ser63) protein expression profile in cells. The kit can be used for measuring the relative amounts of Calsenilin/KCNIP3 (Phospho-Ser63) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calsenilin/KCNIP3 (Phospho-Ser63).
Tissue Specificity	Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-EKC2283-datasheet.pdf

BOS-EKC2283-safety-datasheet.pdf