CDH5 Cadherin 5 Mouse Recombinant Protein

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Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Sterilefiltered colorless solution.
Menge 5ug
ArtNr BOS-PROTP55284
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene name
Cdh5
Conjugate
No
Contents
CDH5 protein solution (0.5mg/ml)contains phosphate buffered saline (pH7.4) and 10% glycerol.
Description
CDH5 produced in Sf9 Insectcells is a single, glycosylated polypeptide chain containing 583 amino acids(25-599a.a.) and having a molecular mass of 66.2kDa. (Molecular size on SDS-PAGEwill appear at approximately 70-100kDa).
CDH5 is expressed withan 8 amino acid His tag at C-Terminus and purified by proprietarychromatographic techniques.
Short description
CDH5 produced in Sf9 Insectcells is a single, glycosylated polypeptide chain containing 583 amino acids(25-599a.a.) and having a molecular mass of 66.2kDa. (Molecular size on SDS-PAGEwill appear at approximately 70-100kDa).
CDH5 is expressed withan 8 amino acid His tag at C-Terminus and purified by proprietarychromatographic techniques.
Uniprot ID
P55284
Purification
Greaterthan 90.0% as determined by SDS-PAGE.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Synonyms
Cadherin-5; Vascular endothelial cadherin; VE-cadherin; CD144; Cdh5;
Protein function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Subcellular localization
Cell junction
Source
Sf9, Insect cells.
Shipping
Shipped with wet ice

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Menge: 5ug
Lieferbar: In stock
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