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CDH5 Cadherin 5 Mouse Recombinant Protein

CDH5 Cadherin 5 Mouse Recombinant Protein

Hersteller

Boster

Kategorie

Typ

Proteins Recombinant

Specific against

other

Format

Solution

Menge

5ug

ArtNr

BOS-PROTP55284

Targets

CD144

eClass 6.1

34160400

eClass 9.0

42020190

Lieferbar

Contents

CDH5 protein solution (0.5mg/ml)contains phosphate buffered saline (pH7.4) and 10% glycerol.

Description

CDH5 produced in Sf9 Insectcells is a single, glycosylated polypeptide chain containing 583 amino acids(25-599a.a.) and having a molecular mass of 66.2kDa. (Molecular size on SDS-PAGEwill appear at approximately 70-100kDa).
CDH5 is expressed withan 8 amino acid His tag at C-Terminus and purified by proprietarychromatographic techniques.

Gene name

Cdh5

Protein function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

Purification

Greaterthan 90.0% as determined by SDS-PAGE.

Shipping

Shipped with wet ice

Short description

CDH5 produced in Sf9 Insectcells is a single, glycosylated polypeptide chain containing 583 amino acids(25-599a.a.) and having a molecular mass of 66.2kDa. (Molecular size on SDS-PAGEwill appear at approximately 70-100kDa). CDH5 is expressed withan 8 amino acid His tag at C-Terminus and purified by proprietarychromatographic techniques.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Cell junction
Format Information	Sterilefiltered colorless solution.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Einfache Bestellung Periodische Bestellung

Menge: 5ug

lieferbar

Lieferung vsl. bis 16.05.2024

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