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GFER Growth Factor, Augmenter of Liver Regeneration Human Recombinant Protein

Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Solution
Menge 10ug
ArtNr BOS-PROTP55789
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Contents
GFER protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
Description
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa.
GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Gene name
GFER
Protein function
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Shipping
Shipped with wet ice
Short description
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa.
GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization
Isoform 1: Mitochondrion intermembrane space.
Tissue specificity
Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
Format Information
Sterile Filtered colorless solution.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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Lieferung vsl. bis 30.05.2024 

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