Hersteller |
Boster
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Solution |
Menge |
10ug |
ArtNr |
BOS-PROTP55789 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Contents |
GFER protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT. |
Description |
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa. GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Gene name |
GFER |
Protein function |
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen. |
Purification |
Greater than 90.0% as determined by SDS-PAGE. |
Shipping |
Shipped with wet ice |
Short description |
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa. GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Storage |
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles. |
Subcellular localization |
Isoform 1: Mitochondrion intermembrane space. |
Tissue specificity |
Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. |
Format Information |
Sterile Filtered colorless solution. |
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