GFER Growth Factor, Augmenter of Liver Regeneration Human Recombinant Protein

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Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Sterile Filtered colorless solution.
Menge 10ug
ArtNr BOS-PROTP55789
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene name
GFER
Conjugate
No
Contents
GFER protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT.
Description
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa.
GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Short description
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa.
GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Uniprot ID
P55789
Purification
Greater than 90.0% as determined by SDS-PAGE.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Synonyms
FAD-linked sulfhydryl oxidase ALR; 1.8.3.2; Augmenter of liver regeneration; hERV1; Hepatopoietin; GFER; ALR, HERV1, HPO;
Protein function
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
Subcellular localization
Isoform 1: Mitochondrion intermembrane space.
Tissue specificity
Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle.
Source
E. Coli
Shipping
Shipped with wet ice

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Menge: 10ug
Lieferbar: In stock
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