Manufacturer |
Boster
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Solution |
Amount |
10ug |
Item no. |
BOS-PROTP55789 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Contents |
GFER protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol and 2mM DTT. |
Description |
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa. GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Gene name |
GFER |
Protein function |
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen. |
Purification |
Greater than 90.0% as determined by SDS-PAGE. |
Shipping |
Shipped with wet ice |
Short description |
GFER Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (1-205 a.a) and having a molecular mass of 26kDa. GFER is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Storage |
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles. |
Subcellular localization |
Isoform 1: Mitochondrion intermembrane space. |
Tissue specificity |
Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. |
Format Information |
Sterile Filtered colorless solution. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.