TIRAP Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein Human Recombinant Protein

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Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Sterile Filtered colorless solution.
Menge 10ug
ArtNr BOS-PROTP58753
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene name
TIRAP
Conjugate
No
Contents
The TIRAP solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
Description
TIRAP Human Recombinant produced in E. coli is a single polypeptide chain containing 244 amino acids (1-221) and having a molecular mass of 26.3 kDa.
TIRAP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Short description
TIRAP Human Recombinant produced in E. Coli is a single polypeptide chain containing 244 amino acids (1-221) and having a molecular mass of 26.3 kDa.
TIRAP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Uniprot ID
P58753
Purification
Greater than 90% as determined by SDS-PAGE.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Synonyms
Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; MyD88-2; TIRAP; MAL;
Protein function
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
Subcellular localization
Cytoplasm
Tissue specificity
Highly expressed in liver, kidney, spleen, skeletal muscle and heart. Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain.
Source
E.coli.
Shipping
Shipped with wet ice

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Menge: 10ug
Lieferbar: In stock
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