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TIRAP Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein Human Recombinant Protein

TIRAP Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein Human Recombinant Protein

Manufacturer	Boster
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Format	Solution
Amount	10ug
Item no.	BOS-PROTP58753
eClass 6.1	34160400
eClass 9.0	42020190
Available
Contents	The TIRAP solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 2mM DTT and 20% glycerol.
Description	TIRAP Human Recombinant produced in E. coli is a single polypeptide chain containing 244 amino acids (1-221) and having a molecular mass of 26.3 kDa. TIRAP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Gene name	TIRAP
Protein function	Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
Purification	Greater than 90% as determined by SDS-PAGE.
Shipping	Shipped with wet ice
Short description	TIRAP Human Recombinant produced in E. Coli is a single polypeptide chain containing 244 amino acids (1-221) and having a molecular mass of 26.3 kDa. TIRAP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Cytoplasm
Tissue specificity	Highly expressed in liver, kidney, spleen, skeletal muscle and heart. Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain.
Format Information	Sterile Filtered colorless solution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

available

Delivery expected until 5/30/2024