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Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag (MALS verified)

Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag (MALS verified)

ArtNr	CA7-H52A9-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 200 ug x 5
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Isotype	IgG1
Konjugat/Tag	Unconjugated, C-mFc
Purity	90%
Formula	20 mM Tris, 150 mM NaCl, pH8.0
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-mFc(mIgG1), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	111.2 kDa
Manufacturer - Format	Powder
Description	Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Background	Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Molecule	Cadherin-17
Exp Region	Gln 23 - Met 787
Characteristics	This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.2 kDa. The protein migrates as 130-135 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.1 EU per μg
Buffer	20 mM Tris, 150 mM NaCl, pH8.0
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CA7-H52A9-100ug-datasheet.pdf

CA7-H52A9-100ug-safety-datasheet.pdf