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NPHP3 Antibody (N-term)

NPHP3 Antibody (N-term)

ArtNr	ABC-AP12751a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NPHP3, KIAA2000, Nephrocystin-3
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Primary Accession	Q7Z494
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.
Bio References	Simpson, M.A., et al. Am. J. Kidney Dis. 53(5):790-795(2009) Tory, K., et al. Kidney Int. 75(8):839-847(2009) Bergmann, C., et al. Am. J. Hum. Genet. 82(4):959-970(2008) Hoefele, J., et al. J. Am. Soc. Nephrol. 18(10):2789-2795(2007) Leipe, D.D., et al. J. Mol. Biol. 343(1):1-28(2004)
Clonality	Polyclonal
Clone/Animal Names	RB32452
Gene ID	27031
Gene Name	NPHP3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	NPHP3 Antibody (N-term) (Cat. #AP12751a) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the NPHP3 antibody detected the NPHP3 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	NPHP3 Antibody (N-term) (Cat. #AP12751a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NPHP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q6AZT7; P0CI65; NP_694972.3
Predicted	Zf, X
Isotype	Rabbit Ig
Calculated MW	150864
Antigen Region	144-173
Antigen Source	HUMAN
Target/Specificity	This NPHP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human NPHP3.
NCBI Accession	NP_694972.3

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Menge: 80 ul

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