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GABPA Antibody (monoclonal) (M04)

ArtNr ABC-AT2140a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, IHC
Clon 1D6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Citations C-Myc is a Nrf2-interacting protein that negatively regulates phase II genes through their electrophile responsive elements. Levy S, et al. IUBMB Life, 2010 Mar. PMID 20232342.Interaction between SNPs in the NRF2 gene and elite endurance performance. Eynon N, et al. Physiol Genomics, 2010 Mar 3. PMID 20028934.Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin. Kim YR, et al. J Pathol, 2010 Mar. PMID 19967722.Nuclear respiratory factor 2 induces the expression of many but not all human proteins acting in mitochondrial DNA transcription and replication. Bruni F, et al. J Biol Chem, 2010 Feb 5. PMID 19951946.Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery. Boros J, et al. Genome Res, 2009 Nov. PMID 19687146.
NCBI NP_001184226.1,NP_002031.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GA-binding protein alpha chain,GABP subunit alpha,Nuclear respiratory factor 2 subunit alpha,Transcription factor E4TF1-60,GABPA,E4TF1A
Similar products GABPA, E4TF1A, GA-binding protein alpha chain, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60, GABP subunit alpha
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Manufacturer - Targets
GABPA (NP_002031, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
Clonality
Monoclonal
Gene Name
GABPA
Subtitle
Mouse monoclonal antibody raised against a partial recombinant GABPA.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IF
WB: 1:500~1000
WB: 1:500~1000
IHC
Org Accession
NP_002031
Gene Description
GA binding protein transcription factor, alpha subunit 60kDa
Gene Summary
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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