Human CCL17 / TARC Protein, Fc Tag (MALS verified)

Protein

RT

34.5 kDa

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

CCL17

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

50 mM Tris, 100mM Gly, 25mM Arginine, 150mM NaCl, pH7.5

trehalose