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Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)

Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)

ArtNr	CD1-H53H3-500ug
Hersteller	ACROBiosystems
Menge	500 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	CHO cells
Konjugat/Tag	Unconjugated
Purity	95%
Formula	20 mM Tris, 150 mM NaCl, pH7.5
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	49.0 kDa
Manufacturer - Format	Liquid
Description	CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.
Background	CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.
Molecule	CD39L1/ENTPD2
Exp Region	Thr 29 - Asp 460
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 36-37 kDa and 57-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	20 mM Tris, 150 mM NaCl, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 3 months under sterile conditions.
Protectant	glycerol

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Arbeitsanleitung (Data Sheet) anfordern

CD1-H53H3-500ug-datasheet.pdf

CD1-H53H3-500ug-safety-datasheet.pdf