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Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein (CD3-CM104)

Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein (CD3-CM104)

ArtNr	CD3-CM104-100UG
Hersteller	KactusBio
Menge	100 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Hematology Leukemia Lymphoma
Format	Liquid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Konjugat/Tag	FLAG, HIS
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice	Yes
Sequence	Gln22-Asp117(CD3E) & Phe22-Ala105(CD3D)
Alias	CD3,CD3e,CD3E,CD3d,T3D,CD3D,CD3E&CD3D,CD3 delta&CD3 epsilon
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	CD3E&CD3D/CD3 epsilon&CD3 delta
Manufacturer - Conjugate / Tag	C-His, C-Flag
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 16.17 kDa (CD3E) and 15.01 kDa (CD3D). Due to glycosylation, the protein migrates to 17-23 kDa and 35-45 kDa based on Bis-Tris PAGE result.
Description	Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein is expressed from HEK293 with Flag tag at the C-Terminus of CD3E and His tag at the C-Terminus of CD3D.It contains Gln22-Asp117 (CD3E) and Phe22-Ala105 (CD3D).
Background	T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E&CD3D, are single-pass type I membrane proteins. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Endotoxin	Less than 0.1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CD3-CM104-100UG-datasheet.pdf

CD3-CM104-100UG-safety-datasheet.pdf