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Human CD8 alpha/CD8A Protein (CD8-HM618A)

Human CD8 alpha/CD8A Protein (CD8-HM618A)

ArtNr	CD8-HM618A-100UG
Hersteller	KactusBio
Menge	100 ug
Quantity options	100 ug 500 ug
Kategorie	Oncology By Cell Type Hematology Leukemia
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Fc
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Sequence	Ser22-Asp182
Alias	CD8a,Lyt-2,CD8,Leu2,MAL,p32,CD8a molecule,OKT8 T-cell antigen
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	CD8 alpha/CD8A
Manufacturer - Conjugate / Tag	C-Llama IgG2b Fc
Shipping Temperature	Shipped at ambient temperature.
Storage Conditions	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 44.92 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Description	Recombinant Human CD8 alpha/CD8A Protein is expressed from HEK293 with Llama IgG2b Fc tag at the C-terminus.It contains Ser22-Asp182.
Background	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Endotoxin	Less than 0.1 EU per μg by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1mg/ml for 500μg or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CD8-HM618A-100UG-datasheet.pdf

CD8-HM618A-100UG-safety-datasheet.pdf