Antibodies

Mouse Anti-Human CASP3 Clone C33 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon C33
Isotype IgG1
Applikationen WB
Menge 100 ug
Host Mouse
ArtNr CS-CMC431
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Mouse Anti-Human Caspase 3 Clone C33 monoclonal antibody. The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro-enzyme that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase 3 consists of large (17 kD) and small (12 kD) subunits which associate to form an active enzyme. The active caspase 3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g. PARP and DFF).
Formulation
Liquid in PBS + 50% glycerol + 0.5 mg/ml BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Recognizes both proform and the cleaved fragments of caspase 3.
Immunogen
Recombinant human caspase 3
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with both human and mouse caspase 3.

Arbeitsanleitung

CS-CMC431.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 1.004,96 €
Preis: 1.004,96 €
lieferbar

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Arne Pelz

sales@hoelzel.de