Mouse Anti-Human Fas Ligand Clone ALF1.2 mAb

Hersteller Cell Sciences
Kategorie Produkte / Antibody
Typ Antibody
Specific against Human
Isotype IgG2a
Applikationen FC, ELISA
Menge 100 ug
ArtNr CS-CMF003
Eclass 6.1 32160702
Eclass 9.0 32160702
Fas ligand (FasL), also known as CD95L, is a member of the TNF family and induces apoptosis via binding to Fas (CD95). The protein exists in two forms, either membrane FasL or soluble FasL, which migrate at molecular weight of 45 kDa and 26 kDa, respectively. FasL is expressed on a variety of cells including activated lymphocytes, natural killer cells and monocytes. Interaction of FasL and Fas plays an important role in physiological apoptotic processes. Malfunction of the Fas-FasL system causes hyperplasia in peripheral lymphoid organs and accelerates autoimmune disease progression and tumorigenesis. ALF1.2 antibody reacts with FasL-transfected cells and recognizes soluble and membrane bound forms of human FasL. Isotype: Mouse IgG2a, Formulation: Purified immunoglobulin in phosphate buffered saline, pH 7.2, with 1% bovine serum albumin. Preservative: 0.1% sodium azide. Purification: Purified from ascites by Protein A/G chromatography. Immunogen: Recombinant soluble, active form of human Fas ligand. Cross-reactivity: Human.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 384,19 €
Preis: 384,19 €

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