Mouse Anti-Human MMP10 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon 9G10
Isotype IgG2
Applikationen WB, IHC
Menge 100 ug
Host Mouse
ArtNr CS-CMM109
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot: (1:1, 000) Immunohistochemistry (Paraffin): (1:50-300) The optimal concentration should be determined by the user for each specific application.
Description
Mouse Anti-Human MMP10 monoclonal antibody. The antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant human MMP-10). Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site;, a short linker region, and a carboxyl terminal hemopexin- like domain.
Formulation
Lyophilized from a 0.2 um sterile filtered solution in PBS
Specificity
Recognizes human MMP10
Immunogen
Recombinant human MMP10
Purification
Protein G affinity chromatography
Reconstitution
Centrifuge vial prior to opening. Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.
Storage and Stability
Lyophilized antibody is stable for at least 2 years from date of receipt at <=-20C. Reconstituted antibody is stable in working aliquots at <=-20C for at least six months. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
No cross-reactivity with other human MMPs

Arbeitsanleitung

CS-CMM109.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 731,98 €
Preis: 731,98 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de