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Mouse Anti-Human MMP-10 (Clone 9G10) mAb

Mouse Anti-Human MMP-10 (Clone 9G10) mAb

Manufacturer	Cell Sciences
Category	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Clone	9G10
Isotype	IgG2
Applications	WB, IHC
Amount	100 ug
Host	Mouse
Item no.	CS-CMM109
eClass 6.1	32160702
eClass 9.0	42030590
Available
Cross-Reactivity	No cross-reactivity with other human MMPs
Description	Mouse Anti-Human MMP10 monoclonal antibody. The antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant human MMP-10). Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site;, a short linker region, and a carboxyl terminal hemopexin- like domain.
Formulation	Lyophilized from a 0.2 um sterile filtered solution in PBS
Immunogen	Recombinant human MMP10
Purification	Protein G affinity chromatography
Reconstitution	Centrifuge vial prior to opening. Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200 ug/ml.
Storage and Stability	Lyophilized antibody is stable for at least 2 years from date of receipt at <=-20C. Reconstituted antibody is stable in working aliquots at <=-20C for at least six months. Avoid repeated freeze-thaw cycles.
Specificity	Recognizes human MMP10

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CMM109.pdf

CS-CMM109-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/23/2024