Antibodies

Mouse Anti-Human NFkB p65 mAb

Kein Verkauf an Patienten, Ärzte, Apotheken oder Privatpersonen! Mehr erfahren

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG1
Applikationen WB
Menge 100 ug
Host Mouse
ArtNr CS-CMN105
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot Immunoprecipitation, Immunohistochemistry
Description
Mouse Anti-Human RELA monoclonal antibody. NFkB is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), proinflammatory cytokines, and viral infection, IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.
Formulation
Liquid in PBS + 1 mg/ml BSA + 1.5 mM sodium azide + 50% glycerol. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Human RELA
Immunogen
Human RELA
Storage and Stability
Store at -20C or in working aliquots at -80C. Avoid repeated freeze-thaw cycles .
Cross-Reactivity
Human, mouse, and rat

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt und Sicherheitsdatenblatt) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Menge: 100 ug
Lieferbar: Out of stock
Fragen zum Produkt?
 
Schließen