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Mouse Anti-Human NFkB p65 mAb

Mouse Anti-Human NFkB p65 mAb

Manufacturer	Cell Sciences
Category	Neuroscience Aging & Neurological Disorders Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Isotype	IgG1
Applications	WB
Amount	100 ug
Host	Mouse
Item no.	CS-CMN105
Targets	RELA, REL
eClass 6.1	32160702
eClass 9.0	42030590
Available
Cross-Reactivity	Human, mouse, and rat
Description	Mouse Anti-Human RELA monoclonal antibody. NFkB is a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), proinflammatory cytokines, and viral infection, IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.
Formulation	Liquid in PBS + 1 mg/ml BSA + 1.5 mM sodium azide + 50% glycerol. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Human RELA
Storage and Stability	Store at -20C or in working aliquots at -80C. Avoid repeated freeze-thaw cycles .
Specificity	Human RELA

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CMN105.pdf

CS-CMN105-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024