Mouse Anti-Human TNF-alpha Clone B-C7 mAb

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Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon B-C7
Isotype IgG1
Applikationen ELISA
Menge 0.5 mg
ArtNr CS-CMT141
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
ELISA system, in vitro, neutralization
Description
Mouse Monoclonal Antibody against Human TNF-alpha, Clone B-C7. TNF-alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. It has also been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. This mAb was produced, in vitro, using serum free medium.
Formulation
Lyophilized from a solution of 0.5 ml PBS + 125 mM trehalose.
Specificity
Blocks TNF-a-induced cytotoxicity on U937 cells. Neutralizes both natural and recombinant human TNF-a and recognizes TNF-a bound to its receptor. The antibody does not bind to rodent TNF-a.
Purification
Ion exchange chromatography.
Reconstitution
Dissolve the contents of the vial by injection of 0.5 ml sterile distilled water.
Storage and Stability
Lyophilized product is stable for at least one year at 4C (expiration date is indicated on the vial). After reconstitution, the contents can be safely stored at 4C for one month or for one year at -20C. Add 0.02% sodium azide to prevent bacterial growth. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

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Menge: 0.5 mg
Lieferbar: In stock
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