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Mouse Anti-Human TNF-alpha Clone B-C7 mAb

Mouse Anti-Human TNF-alpha Clone B-C7 mAb

Manufacturer	Cell Sciences
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis ELISA Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human
Clone	B-C7
Isotype	IgG1
Applications	ELISA
Amount	0.5 mg
Item no.	CS-CMT141
Targets	ACHE, TNF
eClass 6.1	32160702
eClass 9.0	42030590
Available
Description	Mouse Monoclonal Antibody against Human TNF-alpha, Clone B-C7. TNF-alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. It has also been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. This mAb was produced, in vitro, using serum free medium.
Formulation	Lyophilized from a solution of 0.5 ml PBS + 125 mM trehalose.
Purification	Ion exchange chromatography.
Reconstitution	Dissolve the contents of the vial by injection of 0.5 ml sterile distilled water.
Storage and Stability	Lyophilized product is stable for at least one year at 4C (expiration date is indicated on the vial). After reconstitution, the contents can be safely stored at 4C for one month or for one year at -20C. Add 0.02% sodium azide to prevent bacterial growth. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity	Blocks TNF-a-induced cytotoxicity on U937 cells. Neutralizes both natural and recombinant human TNF-a and recognizes TNF-a bound to its receptor. The antibody does not bind to rodent TNF-a.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CMT141-datasheet.pdf

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Amount: 0.5 mg

available

Delivery expected until 5/23/2024