Mouse Anti-Human TLR8 Clone 44B05 mAb

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Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon 44B05
Isotype IgG1
Applikationen WB
Menge 100 ul
Host Mouse
ArtNr CS-CMT157
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
Western Blot FACS analysis
Description
Mouse Anti-Human TLR8 Clone 44B05 monoclonal antibody. The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1 contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFeB and suggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of the TLR family, it induces NFeB signaling upon activation. TLR8 gene contains three exons, two of, which have coding function. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
Formulation
Liquid in PBS, pH 7.2 + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thiomersal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Human TLR8
Immunogen
Recombinant human TLR8
Purification
Protein G purified
Storage and Stability
Store at -20C. For long term storage, aliquot and store at -80C. Avoid repeated freeze-thaw cycles.

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Menge: 100 ul
Lieferbar: In stock
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