Antibodies

Rabbit Anti-Human CASP9 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB, ICC
Menge 100 ug
Host Rabbit
ArtNr CS-CPC124
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunoprecipitation Immunocytochemistry
Description
Rabbit Anti-Human Active Caspase 9 Affinity Purified polyclonal antibody. Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase 9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with procaspase 9 (47 kDa) and APAF1. The complex processes pro-caspase 9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved caspase 9 further processes other caspases including caspase 3 and caspase 6, to initiate a caspase cascade leading to apoptosis. The affinity purified antibody recognizing the active forms of caspase 9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.
Formulation
Liquid in PBS + 50% glycerol + 0.5% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Recognizes only the cleaved human Caspase 9 (37 kDa). It does not recognize full length Caspase 9 or any other caspases.
Immunogen
Synthetic peptide mapping to the N-terminus adjacent to Asp330 of human Caspase 9
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles .

Arbeitsanleitung

CS-CPC124.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 1.247,61 €
Preis: 1.247,61 €
lieferbar

Angebot anfordern

Fragen zum Produkt?

Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de