|
Hersteller |
Cell Sciences
|
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Human |
|
Isotype |
IgG |
|
Applikationen |
WB |
|
Menge |
100 ug |
|
Host |
Rabbit |
|
ArtNr |
CS-CPC130 |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
Western Blot |
| Description |
Rabbit Anti-Human Active Caspase 6 Affinity Purified polyclonal antibody. The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase 6 is synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase 3, caspase 6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors BCL2 and BCL-xL. Caspase 6 has also been shown to be involved in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A. |
| Formulation |
Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only. |
| Specificity |
Detects the large subunit (18 kDa) of the active Caspase 6. Does not recognize other caspases. |
| Immunogen |
Synthetic peptide surrounding amion acids mapping to the C-terminus of the large fragment of human Caspase 6 |
| Purification |
Biospecific affinity chromatography |
| Storage and Stability |
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles. |
| Cross-Reactivity |
Reacts with human, mouse, and rat. |
