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Rabbit Anti-Human CASP6 Active Affinity Purified pAb

Rabbit Anti-Human CASP6 Active Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Apoptosis Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPC130
Targets	CASP6, KLK6, CTSB
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with human, mouse, and rat.
Description	Rabbit Anti-Human Active Caspase 6 Affinity Purified polyclonal antibody. The caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase 6 is synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase 3, caspase 6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors BCL2 and BCL-xL. Caspase 6 has also been shown to be involved in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amion acids mapping to the C-terminus of the large fragment of human Caspase 6
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	Detects the large subunit (18 kDa) of the active Caspase 6. Does not recognize other caspases.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CPC130.pdf

CS-CPC130-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024