Rabbit Anti-Human GNAI2 pAb

Hersteller Cell Sciences
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 200 ug
ArtNr CS-CPG201
eClass 6.1 32160702
eClass 9.0 32160702
The tested titer for Western blot is 1:5, 000. The Ab can also be used for immunoprecipitation.
This polyclonal antibody, which reacts with the Gai2 protein, was generated using, E. coli, expressed human Gai2 (a.a. 231-351) as an immunogen. Gai2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gai3 and Gai1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gai2 is expressed widely in tissues and cell lines. Activation of PLC-b by Gaicoupled receptors is the result of release of Gbg subunits from Gai. Gai2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.
Protein A purified rabbit IgG, 200 mg, with 0.1% sodium azide, lyophilized.
Reconstitute to 1 mg/ml by adding 200 ul PBS.
Storage and Stability
4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze and thaw cycles.
Cross-reacts with Gai3, and partially with Gai1.
Menge: 200 ug
Lieferbar: In stock
Listenpreis: 404,42 €
Preis: 404,42 €


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