|
Hersteller |
Cell Sciences |
|
Kategorie |
|
|
Typ |
Antibody |
|
Specific against |
Human |
|
Isotype |
IgG |
|
Applikationen |
WB |
|
Menge |
100 ug |
|
Host |
Rabbit |
|
ArtNr |
CS-CPM107 |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Applications |
WB: working dilution of 0.5-4 ug/mL. The optimal concentration should be determined by the user for each specific application. |
| Description |
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of Neutrophil azurophilic granules. Produced as a single chain precursor, MPO is subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of Neutrophils. MPO is a peroxidase enzyme and lysosomal protein stored in azurophilic granules of the Neutrophils. Since Human MPO has a heme pigment, it causes the green color in secretions rich in neutrophils. |
| Formulation |
Liquid in PBS + 30% Glycerol + 0.5% BSA + 0.01% Thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only. |
| Specificity |
Recognizes 60-100 kDa MPO |
| Immunogen |
Synthetic peptide surrounding amino acid 765 of Human MPO |
| Purification |
Biospecific affinity chromatography |
| Storage and Stability |
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles. |
| Concentration |
0.5 mg/mL |
| GeneID |
4353 |
| Cross-Reactivity |
Reacts with Human, Mouse, and Rat |
