Rabbit Anti-Hu/Mo/Rt MPO pAb

Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of Neutrophil azurophilic granules. Produced as a single chain precursor, MPO is subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of Neutrophils. MPO is a peroxidase enzyme and lysosomal protein stored in azurophilic granules of the Neutrophils. Since Human MPO has a heme pigment, it causes the green color in secretions rich in neutrophils.

Synthetic peptide surrounding amino acid 765 of Human MPO

Recognizes 60-100 kDa MPO