Antibodies

Mouse Anti-Mouse LBP Clone biG 35 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Clon biG35
Isotype IgG1
Applikationen WB, ELISA
Menge 100 ug
ArtNr CS-CML005
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Applications
ELISA: binding titer for ELISA: > 1:20, 000. LBP inhibition studies: no inhibition of LPS binding to membrane bound CD14. Western Blot. The optimal concentration should be determined by the user for each specific application.
Description
Mouse monoclonal antibody against mouse LMP clone biG 35 LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).
Formulation
Lyophilized in PBS with no preservatives or additives
Host info
LBP Knockout Mouse
Immunogen
Immunoaffinity purified recombinant mouse LBP
Purification
Protein G purified
Reconstitution
Centrifuge vial prior to opening. Add 100 ul distilled water to obtain 1 mg/ml.
Storage and Stability
Long term storage at -20C or -80C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/ml
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 537,87 €
Preis: 537,87 €
lieferbar

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