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Mouse Anti-Mouse VEGF Clone MAB0705 mAb

ArtNr CS-CMV122
Hersteller Cell Sciences
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Applikationen WB
Clon MAB0705
Specific against Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products VEGF, VPF, RP1-261G23.1, MGC70609, MVCD1, vascular permeability factor, vascular endothelial growth factor A, OTTHUMP00000165987, OTTHUMP00000224107
Lieferbar
Storage Conditions
Stable for at least 2 years from date of receipt at -20C. After reconstitution, store in working aliquots at -80C for at least 6 months. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Human VEGFA
Description
Vascular Endothelial Growth Factor A (VEGFA) is a member of the PDGF/VEGF growth factor family and is often found as a disulfide linked homodimer. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of VEGFA is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGFA have been associated with proliferative and non-proliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Formulation
Lyophilized from sterile filtered solution in PBS
Immunogen
Recombinant Human VEGFA
Purification
Protein G chromatography
Reconstitution
Centrifuge vial prior to opening. Add PBS to the vial to fully solubilize the antibody.
Specificity
Recognizes Mouse VEGFA

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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