Rabbit Anti-Mouse Bad Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPB114
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunoprecipitation Immunohistochemistry
Description
Rabbit Anti-Mouse BAD Affinity Purified polyclonal antibody. The BCL2 family proteins function to either inhibit (BCL2 and BCL-xL) or promote (BAX and BAD) apoptosis. Similar to other family members, BAD also exhibits sequence homology to BCL2. BAD can selectively dimerize with BCL-xL and BCL2, but not with BAX, BCL-xs, MCL1, or itself. In mammalian cells, BAD binds more strongly to BCL-xL than BCL2. This may explain why BAD reverses the death repressor activity of BCL-xL, but not that of BCL2.
Formulation
Liquid in PBS, pH 7.2 + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Detects the 22 kDa BAD protein. Does not cross-react with related family members.
Immunogen
Synthetic peptide surrounding amino acid 115 of mouse BAD
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Cross-Reactivity
Reacts with human, mouse, monkey, and rat.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 643,38 €
Preis: 643,38 €
lieferbar

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Arbeitsanleitung

CS-CPB114.pdf