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Rabbit Anti-Mouse Bad Affinity Purified pAb

Rabbit Anti-Mouse Bad Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPB114
Targets	BAD
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with human, mouse, monkey, and rat.
Description	Rabbit Anti-Mouse BAD Affinity Purified polyclonal antibody. The BCL2 family proteins function to either inhibit (BCL2 and BCL-xL) or promote (BAX and BAD) apoptosis. Similar to other family members, BAD also exhibits sequence homology to BCL2. BAD can selectively dimerize with BCL-xL and BCL2, but not with BAX, BCL-xs, MCL1, or itself. In mammalian cells, BAD binds more strongly to BCL-xL than BCL2. This may explain why BAD reverses the death repressor activity of BCL-xL, but not that of BCL2.
Formulation	Liquid in PBS, pH 7.2 + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 115 of mouse BAD
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	Detects the 22 kDa BAD protein. Does not cross-react with related family members.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CPB114.pdf

CS-CPB114-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024